产品货号：
Z28260
中文名称：
TOP2A抗体
英文名称：
Anti-TOP2A Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TOP2A Antibody |
| 指标别名 | DNA topoisomerase 2 alpha;TOP2;TOP2A;TOP2A-Specific;TP2A |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB |
| 基因名称 | TOP2A |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 计算分子量 | 174KD |
| 成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| 纯化方式 | Immunogen affinity purified |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | The human topoisomerase II enzyme is encoded by a single-copy gene which is mapped to 17q21-q22.The TOP2A gene spans approximately 30kb and contains 35 exons.Furthermore,DNA topoisomerases are enzymes that control and alter the topologic states of DNA in both prokaryotes and eukaryotes.Topoisomerase II from eukaryotic cells catalyzes the relaxation of supercoiled DNA molecules,catenation,decatenation,knotting,and unknotting of circular DNA.It appears likely that the reaction catalyzed by topoisomerase II involves the crossing-over of 2 DNA segments.There are about 100,000 molecules of topoisomerase II per HeLa cell nucleus,constituting about 0.1% of the nuclear extract1.DNA topoisomerase II-alpha is associated with the pol II holoenzyme and is a required component of chromatin-dependent coactivation.Specific inhibitors of topoisomerase II blocked transcription on chromatin templates,but did not affect transcription on naked templates.Addition of purified topoisomerase II-alpha reconstituted chromatin-dependent activation activity in reactions with core pol II2. |
| Uniprot ID | P11388 |
| 基因名全称 | DNA topoisomerase 2-alpha |
| 推荐稀释比 | WB,1:500～1:2000 |
相关搜索：TOP2A抗体，TOP2A多抗，Anti-TOP2A Antibody